Learning, memory and behavior depend on the continuous movement of valuable cellular components along axons, narrow nerve fibers through which neurons send signals to other neurons. But when this transport system fails, molecular traffic jams can cause neuronal damage associated with diseases like Alzheimer's, Parkinson's and prion disorders. In this Front Row lecture, Scripps Research associate professor Sandra Encalada will share how her lab is unraveling the cellular pathways that lead to the formation of toxic protein clumps seen at traffic jams inside brain cells undergoing neurodegeneration. Her breakthroughs are transforming the way scientists view brain health and identifying new molecules that could treat, and even reverse, complex neurological conditions.
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ABOUT SCRIPPS RESEARCH
Scripps Research is an independent, nonprofit biomedical institute ranked the most influential in the world for its impact on innovation. Based in La Jolla, California, we are advancing human health through profound discoveries that address pressing medical concerns around the globe.